Saturday, 15 April 2017

Rx Product News

INDICATION: Allergan has announced the FDA approval of Rhofade cream, which is indicated for the topical treatment of persistent facial erythema (redness) associated with rosacea in adults.
DOSAGE FORM: Topical cream: once-daily application

 Adapt Pharma
INDICATION: The FDA has approved Narcan Nasal Spray (concentrated naloxone) as a 2-mg formulation for the emergency treatment of known or suspected opioid abuse, as manifested by respiratory and/or central nervous system depression.
DOSAGE FORM: Nasal spray: 2 and 4 mg

 Ironwood and Allergan
INDICATION: The FDA has approved a 72-mcg dose of Linzess (linaclotide) for the treatment of chronic idiopathic constipation (CIC) in adult patients. Linzess is now approved in 3 dosage strengths: 290 mcg for adult patients with irritable bowel syndrome with constipation, and 145 mcg and the new 72 mcg for adults with CIC.
DOSAGE FORM: Capsules: 72, 145, and 290 mcg

Marathon Pharmaceuticals, LLC
INDICATION: The FDA has approved Emflaza (deflazacort) tablets and oral suspension for the treatment of Duchenne muscular dystrophy in patients 5 years and older.
DOSAGE FORM: Tablets (6, 18, 30, and 36 mg) and oral suspension (22.75 mg/mL)

Source: Pharmacy Times (March Issue)

Sunday, 26 March 2017

Career in Pharmacogenetics in Psychiatry

Pharmacogenetics has the potential to radically change the practice of psychiatry. Since the advent of psychopharmacology, psychiatrists and pharmacists have struggled with a set of baffling treatment outcomes: so-called idiosyncratic drug reactions, drug sensitivities
, or, conversely, patients who require high doses of medication for a modest clinical benefit. As the science of pharmacogenetics has emerged over the past several years, professionals are now beginning to understand why some people in the real world react to medications far differently than clinical trial data would suggest.
Those who work in this field can see a future in which psychotropics are tailored to the patient; indeed, many findings can be applied in clinical practice right now. Other pharmacogenetics applications are not quite ready for standard care, and patients with mental health disorders may be filling in our knowledge gaps with misinformation. Pharmacists can play a key role in helping patients navigate this new world of psychopharmacogenetic testing.

Monday, 9 January 2017


Image result for sports pharmacyParticipation in sport and exercise is undertaken at all levels, from amateur enthusiasts to elite athletes. Pharmacists are frequently approached by people who engage in sport and exercise for advice about drug treatment or on general healthcare associated with their participation in sport. There is a growing need for specialist pharmacists in the area of sport and exercise in order to fulfil this valuable healthcare role. These specialists may be described as sports pharmacists.

In this article the authors will draw on their recent experiences of working with pharmacists in a sport-orientated environment and then speculate on how these experiences may be used to develop the concept of sports pharmacists on an international scale.

The London 2012 Olympic and Paralympic Games
The 2012 Olympic and Paralympic Games were awarded to the City of London in 2005. The London Organising Committee for the Olympic and Paralympic Games (LOCOG) was established to plan and deliver the Games.


With a Bachelor of Science in Pharmacy (BScPharm) degree, you’ll have a wide range of career opportunities. The majority of graduates enter community pharmacy practice. You might also find working in a hospital pharmacy an interesting challenge, particularly in view of pharmacists’ expanding role within the clinical setting. As well, the pharmaceutical industry provides opportunities for pharmacists in the fields of sales and marketing, production, research, and quality control.
  1. Pharmacist
  2. Pharmaceutical sales
  3. Drug researcher
  4. Clinical specialty practices in such areas as infectious diseases, pediatrics, psychiatry, intensive care, or cardiology
  5. Policy maker or advisor in federal or provincial government, regarding drug products and pharmacy practice
  6. Lawyer, journalist or consultant specializing in pharmaceutical issues.
  7. Academic Pharmacy
  8. Ambulatory Care Pharmacist
  9. Community Pharmacy
  10. Consultant Pharmacy
  11. Federal Pharmacy - Armed Services
  12. Federal Pharmacy - Public Health
  13. Hospital and Institutional Pharmacy
  14. Informatics
  15. Managed Care Pharmacy
  16. Pharmaceutical Sciences/Industry

The increased role of federal and provincial governments in public health has provided opportunities for pharmacists in analytical laboratories and in administrative positions as consultantsgovernment inspectors, and health officers. Opportunities are also available in universities as teachers and researchers.
If you wish to practice as a licensed pharmacist, you’ll need a Bachelor of Science in Pharmacy (BScPharm). If you wish to teach or do research, a Master of Science (MSc) degree or further postgraduate study is usually required.
In a self-reporting poll, 100% of 2010 graduates from Dalhousie’s College of Pharmacy were employed upon graduation. Some of their careers include:

Friday, 6 January 2017

Oncology pharmacist : The cancer counsellor

Davina Lau is lead pharmacist, oncology, at London Bridge Hospital, a private hospital owned by HCA Healthcare UK.

Why did you decide to go into hospital pharmacy?

I had a taste of hospital pharmacy as an intern pharmacist (preregistration trainee) in New Zealand so when an opening for a hospital position in Australia came up with an oncology rotation, I applied for it. Back then, few pharmacists were interested in oncology and interns were a novelty because there were so few of us. I went into hospital pharmacy primarily because I was interested in oncology — it was different from what we were exposed to as students and interns.

How and why did you become an oncology specialist?

I spent several years working in different hospitals in different countries as an oncology, haematology, aseptic and palliative care pharmacist. I also undertook postgraduate courses and attended plenty of after-hour lectures, seminars and conferences in oncology and haematology. I was interested in oncology because I believed it was where a pharmacist could make a significant impact on the wards.
Oncology patients have limited chances at fighting their disease, and every opportunity they have is an important one. As patients come back for their treatments every fortnight or every three weeks, you build a relationship with them and their families and it becomes a personal journey for the pharmacist too. You become an unofficial counsellor, proverbial punching bag and cheerleader, as well as being their pharmacist. Survival rates have increased since I was an intern, and it is gratifying to be able to tell patients that we have a plethora of agents now to help them fight their disease.

What are your responsibilities and typical tasks in your current role?

Our team is relatively small so my role still requires me to complete operational tasks on most days. With the help of senior oncology pharmacists, I oversee the daily running of the inpatient ward, aseptic suite, chemo day unit and any oncology-associated processes in the dispensary.
As an independent prescriber in the chemotherapy day unit, I see patients and assess their side effects related to chemotherapy. If an existing treatment is being continued, I prescribe medicines within my scope of practice. If I need a second opinion, I contact the consultant to discuss options. Once decided, I prescribe according to the outcome of our discussion. This includes chemotherapies with doses that change depending on renal or hepatic function. Everything is documented on MOSAIQ (our electronic prescribing system) so that there is an accessible audit trail.

Thursday, 22 December 2016

Theories and Mechanism of dissolution

In order for an active pharmaceutical ingredient to be bioavailable, it has to be dissolved. Thus, solubility and dissolution measurements are  necessary requirements to estimate the drugs bioavailability:
  • In theory, the intrinsic dissolution rate (IDR) is proportional to the solubility of the compound – i.e. in many cases a very good estimate of IDR can be obtained directly from a solubility measurement: Low solubility = low IDR and vice versa.
  •  It also implies that the dissolution rate is proportional to the solubility (but here the particle size/the surface area of the particles should also be taken into account).
  • However, in some cases the liberation af molecules from the surface into water is not ideal – and the dissolution rate will be lower or higher than theoretically calculated. Thus, in order to determine whether your compound behaves ”ideal”, a measurement of IDR is neccessary.

Click here for learning more about theories and mechanism of dissolution in detail.

How to be a FDA Inspector: Pharma Oppurtunity

FDA auditors -- also known as FDA inspectors -- have many responsibilities. They investigate complaints of illness, injury, and death related to food, develop new inspection procedures, plan, and direct food regulatory programs, advise officials on policies and regulations, and take action against FDA violations. As such, an FDA auditor is someone who has a balance of specific education and specific work experience. He is not only educated regarding aspects of chemistry, biology, and medicine but already has experience as a food inspector prior to joining the FDA.
Complete your education
There is not a specific degree requirement, but in order to be an FDA Inspector, you will need to have at least a bachelor's degree with at least 30 credit hours in some combination of biology, chemistry, nutrition, food technology, medical science, engineering, and pharmaceutical medicine. A master's degree or higher in one of the above subjects can also help you to secure a higher position with the FDA.

Complete classes in statistics 
Classes that include the theory, principles, or application of computer programming or computers. Up to 8 credit hours of such classes can contribute to the 30 credit-hour requirement above, and can better prepare you for some of the computer work you will be doing for the FDA.
Gain food inspection experience
Before becoming an FDA inspector, you can still inspect food in other capacities. Many major food corporations hire quality managers to make sure that their food meets the guidelines set by the FDA. This will give you direct, on-the-job training and practical experience as it relates to food inspection, which is the best preparation you can have for what you will be doing with the FDA.
Find jobs through This website is where the government posts all openings, including those for FDA Auditors.When you have found the job(s) you wish to apply for, submit your resume, cover letter, and any other requested material through the website.